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Rams should handle 49ers

Week 10 NFL odds, lines, best bets, predictions: Computer model likes Buccaneers and 49ers

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 on a sizzling 47-29 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Covers.com · 17h

Rams vs 49ers Predictions, Picks & Best Bets for NFL Week 10

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NFL Week 10 preview: Rams vs. 49ers

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Bills at Dolphins: Predictions, picks and odds for NFL Week 10 game

The Buffalo Bills (6-2) visit the Miami Dolphins (2-7) at Hard Rock Stadium in Miami Gardens for a Week 10 showdown, and USA TODAY's panel of NFL experts have locked in their picks and predictions for...

· 15h

NFL 2025 Week 10 odds: Jaguars vs. Texans spread, line, over/under

Las Vegas Sun · 1d

Vegas pick'em: NFL Week 10 winners against the spread

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Browns vs. Jets prediction, pick, odds for Sunday's NFL Week 10 game - 11/9/2025

Pick ATS: Jets (+2.5)

· 15h

NFL 2025 Week 10 odds: Colts vs. Falcons spread, line, over/under

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NFL 2025 Week 10 odds: Buccaneers vs. Patriots spread, line, over/under

Player the 49ers should have gotten at the trade deadline

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· 2d

Kurtenbach: The 49ers sat out the NFL trade deadline. Fans will eventually thank them

General Manager John Lynch and his crew did exactly what they should have done.

Niners Wire on MSN · 1d

Kyle Shanahan explains why 49ers were quiet at the NFL trade deadline

· 1d · on MSN

49ers have as many sacks as one NFL player. Shanahan explains D-line inactivity at deadline

1don MSN

Fantasy football managers might need to panic about this 49ers player

George Kittle has just 75 yards in the three games that he has played since returning from an injury that sidelined him for five games. It has fantasy football

14hon MSN

NFL Week 10 bold predictions & key matchups: Maye vs. Mayfield, hoss fight NFC showdown, can 49ers survive the Rams?

YouTube Nate Tice & Charles McDonald dive into the Week 10 NFL slate with bold predictions, matchups to watch and more. The two hosts start off by getting Lost in the Sauce with their three favorite games of the week,

USA TODAY Touchdown Wire on MSN

49ers address their biggest need in new 2026 NFL mock draft

The San Francisco 49ers have had a rough nine weeks getting after the quarterback, so they may consider adding another edge rusher in the first round.

20h

Tom Brady on Bay Area Homecoming: A Special Win Against the 49ers

NFL legend Tom Brady recounts one of his favorite games from his playing career: a memorable trip back to the Bay Area to play the San Francisco 49ers in 2016. He talks about going home to California,

1don MSN

Former 49ers Linebacker From Famous Football Family Dies Unexpectedly

A former 49ers, Raiders, Chargers, and Buccaneers linebacker whose brothers and son played in the NFL has died.

Niners Wire on MSN

Giants QB Jaxson Dart credits 49ers fans for ‘lopsided’ noise at MetLife Stadium

The San Francisco 49ers traveled 3,000 miles for a battle with the New York Giants on Sunday, and their fans made themselves heard at MetLife Stadium.