Bethesda, MD – Scientists have identified a new, longer species of amyloid β-peptide that has the potential to be a new target for the treatment of Alzheimer's disease. The research appears as the ...

Amyloid β is the cleavage product of Amyloid Precursor Protein (APP). Long suspected a culpable player in Alzheimer disease progression due to the plaques it forms, Aβ may have a physiological role ...

Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of ...

The paper T. Liu et al., “The amyloid precursor protein is a conserved Wnt receptor,” eLife, 10:e69199, 2021. Amyloid precursor protein, which generates amyloid-β when broken down, has long been ...

Alzheimer's disease is likely caused by stalled protein processing in the brain, according to a new study. The research, ...

An estimated 50 million people worldwide have dementia, with Alzheimer's disease—accounting for more than 70%—being the representative neurodegenerative brain disorder. A Korean research team has, for ...

A protein notorious for its role in Alzheimer’s disease may hold the key to supercharging the aging immune system, according to new research. Scientists have found that a byproduct of amyloid-beta ...

The structure of C99 in a micelle (depicted as the sphere -- a type of model membrane) is illustrated as a ribbon diagram that traces the protein backbone. This structure was determined using nuclear ...

At first glance, Alzheimer's disease and cancer have little in common. One erodes memory, while the other consumes the body. Yet researchers at MUSC Hollings Cancer Center have discovered an ...

Previous research has implicated fungi in chronic neurodegenerative conditions such as Alzheimer’s disease, but there is limited understanding of how these common microbes could be involved in the ...