The COVID-19 pandemic sweeping through the globe has led to enormous efforts to understand the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes the disease. One effort toward ...
Researchers from Tokyo Medical and Dental University (TMDU) identify a novel phosphorylation site of the protein Ulk1 to be an essential regulating factor for alternative autophagy, but not canonical ...
Upon autophagy induction, ZDHHC13 is recruited to autophagosome formation sites together with ATG9A. ULK1 is palmitoylated at Cys 927 and Cys 1003 residues by ZDHHC13, and the ULK1 complex are ...
Unc-51-like autophagy-activating kinases 1 and 2 (ULK1/2) are enzymes that play a key role in initiating and regulating autophagy, with ULK1/2 autophagy being an adaptive stress response to multiple ...
SAN DIEGO--(BUSINESS WIRE)--Endeavor BioMedicines, a clinical-stage precision medicine company targeting the core drivers of multiple terminal diseases including oncology and fibrosis, today announced ...
Autophagy is a vital process in which the body’s cells “clean out” any unnecessary or damaged components. It may be possible to induce autophagy, but there may be associated risks. Researchers have ...
WALTHAM, Mass.--(BUSINESS WIRE)--Deciphera Pharmaceuticals, Inc. (NASDAQ: DCPH), a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines to improve ...
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