BK channels (large-conductance, Ca2+-dependent K+ channels) are essential for the regulation of important biological processes such as smooth muscle tone and neuronal excitability. New research shows ...
In 2004, Washington University in St. Lous researcher Jianmin Cui was handed a puzzling clue to the structure of an ion channel his lab had been studying for five years. Scientists at the Cleveland ...
Potassium channels are critical structures in biology; they selectively allow potassium ions to pass through the membrane surrounding cells. The precise gating of that channel is essential to its ...
LONDON, July 25, 2024 (GLOBE NEWSWIRE) -- Kaerus Bioscience Ltd. (www.kaerusbio.com), a clinical-stage biotechnology company focused on developing therapeutics for rare genetic syndromes of ...
Even though the pore of the BK channel appears always open to potassium ions (red dots), because the pore is hydrophobic, it creates a vapor barrier (red circle) shutting off the flow of ions...most ...
Researchers have discovered a new mechanism for potassium channel inhibitor entry, which could improve the specificity of drugs targeting the channel. Upon binding to calcium ions, BK channels allow ...
Scientists have discovered that an ion-channel mutation that causes epilepsy may do so by making part of the channel protein stiffer, so that the channel toggles open more easily. This is the first ...
LONDON, March 11, 2025 (GLOBE NEWSWIRE) -- Kaerus Bioscience (www.kaerusbio.com), a clinical-stage biopharmaceutical company created by Medixci for the development of therapeutics for rare genetic ...
Building on their pioneering 2018 research into how some of the body's cells, such as neurons and cardiac tissue, communicate via ions that flow through cellular channels, chemists at the University ...
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