To evaluate the role of Hh signalling in CML, Reya and colleagues developed mice that lacked expression of smoothened (SMO), the transmembrane protein that transmits Hh signals, in haematopoietic ...
March 12, 2003 — Imatinib mesylate (Gleevec) is now considered the new gold standard for first-line therapy of chronic myeloid leukemia (CML), according to results of a randomized trial published in ...
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