Doudna lab finds chromosome loss from CRISPR-Cas9 is common—and swapping steps is key to stopping it
When it comes to solving math problems, the order of operations matters (PEMDAS, from left to right!). That appears to be the case for engineering T cells with CRISPR-Cas9, too, as new research from ...
Data presented in a late-breaking presentation at the American Heart Association (AHA) Scientific Sessions 2025- -Phase 1 ...
In the present study, we investigated whether electroporation could be used for one-step multiplex CRISPR/Cas9-based genome editing, targeting IL2RG and GHR in porcine embryos. First, we evaluated and ...
Vertex and CRISPR Therapeutics’ dream of getting the first-ever CRISPR gene editing therapy approved now seems within reach as the candidate aced primary endpoints in a pair of phase 3 trials mere ...
On December 8, the U.S. Food and Drug Administration approved the world’s first CRISPR/Cas9 gene-editing therapy (SN: 12/8/23). The treatment, called Casgevy, targets sickle cell disease by helping ...
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