Nearly all vital functions in the human body are regulated by so-called G protein-coupled receptors on the cell surface. These receptors thus serve as attractive drug targets to treat various diseases ...

Ten years ago, three research teams published a breakthrough — the first description of the molecular mechanism for transduction in fingertip sensory Merkel cells that can transduce gentle touch, a ...

Proteins that act like air traffic controllers, managing the flow of signals in and out of human cells, have been observed for the first time with unprecedented detail using advanced microscopy ...

Bacteria are constantly moving with the help of motility organs called flagella or pili to colonize new niches. Also, ...

Researchers say findings could lead to breakthroughs in tissue repair and regenerative medicine, as well as advanced medical ...

Researchers from Karolinska Institutet have discovered that the genes encoding our T cell receptors vary greatly between persons and populations, which may explain why we respond differently to for ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

A new study published in Brain Sciences provides evidence that dopamine promotes movement by directly altering the excitability of key neurons in the brain’s motor circuitry. The research identifies a ...

Alphaviruses are enveloped RNA viruses that cause disease in humans ranging from acute febrile illness with rash and arthritis to lethal encephalitis. Like many other mosquito-borne viruses, they ...

By looking closely at how peptides interact with joint structures, we can better understand their potential role in supporting cartilage regeneration, reducing inflammation, and improving range of ...