Chloride channels and antiport mechanisms are pivotal for maintaining cellular ion homeostasis and regulating physiological processes such as muscle contraction, epithelial fluid transport and ...

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out ...

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out ...

Researchers have found that a primitive type of ion channel similar to those found in mammalian nerve cells helps bacteria resist the blast of acid they encounter in the stomach of their hosts. The ...

Scientists identified a previously unknown chloride ion channel, which they named alkaliphile (Alka), as a taste receptor for alkaline pH. The sense of taste is among the first to come into contact ...

Credit: Shutterstock. NMD670 is a first-in-class small molecule inhibitor of the skeletal muscle specific chloride ion channel. The Food and Drug Administration (FDA) has granted Orphan Drug ...

Aarhus, Denmark, 25 March 2025 – NMD Pharma A/S, a clinical-stage biotech company dedicated to developing novel and improved treatments for patients living with neuromuscular diseases, today announces ...

BRIGHTON, England--(BUSINESS WIRE)--Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of patients ...

BioRxiv (2023) PubMed PMID: 37546940; PubMed Central PMCID: PMC10402079. The mammalian innate immune system uses cyclic GMP–AMP synthase (cGAS) to synthesize the cyclic dinucleotide 2′,3′-cGAMP during ...

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out ...