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College football odds, picks, predictions for Week 10, 2025

College football picks, predictions against the spread for Week 10 matchups

A total of 30 teams in the Power 4 – including Notre Dame – have two losses or less heading into Week 10 of the college football season.

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2025 college football picks, Week 9 odds, predictions by proven expert: This parlay returns almost +600

College Football Week 10 Top 25 Picks, Odds, Box Score Predictions, Rankings, Schedule

Virginia vs. Cal prediction and betting odds | November 1, 2025

The No. 15 Virginia Cavaliers (7-1) hit the road for an ACC battle against the California Golden Bears (5-3) on Saturday, November 1, 2025 at California Memorial Stadium.

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UTEP vs Kennesaw State Prediction, Picks & Odds for October 28 — College Football Week 10

East Carolina vs. Temple prediction and betting odds | November 1, 2025

Vanderbilt vs Texas Predictions - Early Picks & Odds for Week 10

Vandy leads the nation in EPA per play on offense and hasn’t averaged less than 5.0 yards per play in any game this season.

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Miami (FL) vs. SMU prediction and betting odds | November 1, 2025

Illinois vs. Rutgers prediction and betting odds | November 1, 2025