During a search for keratinocyte differentiation-related genes, we obtained a cDNA fragment from the 5'-untranslated region of a previously identified splicing variant of desmoglein 3 (Dg3). This ...

As skin ages, it slowly loses its ability to renew and protect. The outermost layer, called the epidermis, becomes thinner. This change weakens the skin’s natural barrier and raises the risk of injury ...

It’s sunburn season. Many of us have experienced the pain and peeling that comes from unprotected time in the sun, but we may not focus on a remarkable and vital part of the process: the regeneration ...

Skin injury results when the skin to adhesive attachment is stronger than skin cell to skin cell attachment. As a result, the epidermal layers separate or the epidermis separates completely from the ...

Perhaps best known as a immune-system boost or antidote to scurvy, vitamin C has been found to rejuvenate aging skin by reactivating genes responsible for cell growth. By promoting DNA demethylation, ...

Epidermal hyperproliferation is a major characteristic of psoriasis. The underlying cause of the aberrant keratinocyte growth control is thought to be the presence of activated T lymphocytes at the ...

"Somehow, the epidermal cell layer is able to entrain inner cell layers," Dixit said. "The epidermis is not a passive skin, but instead a mechanical coordinator of the growth of the entire organ." Now ...

How Does the Skin Barrier Work? If you looked at the stratum corneum under a microscope, it’s sort of takes after brick and mortar. It’s made up of cells called corneocytes that act as bricks. These ...

Tiny folds anchoring human skin, called 'rete ridges,' form soon after birth. They show an early-life window that could reshape aging.

The outer layer of skin, the epidermis, is constantly turning over to replace dead or damaged cells throughout our lifetime. Skin stem cells need to continuously make decisions: either make more ...