“It’s genuinely surprising that the add-on gives vancomycin any ability at all to hit gram negatives,” says Kim Lewis, an ...

Gram-negative bacteria, notorious for their intrinsic and acquired resistance mechanisms, pose a significant threat to public health. The emergence of ...

• Require X (hemin) and/or V (nicotinamide adenine dinucleotide) factors for growth • Responsible for 0.5–1% of all cases of IE • Haemophilus aphrophilus is the most common species responsible for IE ...

Antimicrobial resistance has become one of the greatest threats to public health, with rising resistance to carbapenems being a particular concern due to the lack of effective and safe alternative ...

Hospital uptake of newer antibiotics to treat multidrug-resistant gram-negative bacteria was low over a 5-year period, according to a retrospective cohort study. Fully 41.5% of episodes of ...

Gram-negative bacteria deploy a range of protein toxins as mediators of inter-bacterial competition and pathogenicity. Among these, colicins comprise a class of ribosomally synthesised bacteriocins ...

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut ...

A mineral-hogging fungus can “bully” bacteria into becoming more antibiotic resistant, according to new work published June 20 in the journal PLOS Biology by Fred Hutch Cancer Center scientists. The ...

A team led by Paul Hergenrother at the University of Illinois Urbana-Champaign has discovered a new antibiotic that exclusively targets gram-negative bacteria and avoids wiping out the ecosystem of ...

The UK turns to artificial intelligence (AI) to reverse the rising numbers of infections that shrug off antibiotics.

Expert Rev Anti Infect Ther. 2010;8(8):879-885. We recommend a thorough evaluation of patients with non-HACEK Gram-negative endocarditis to assess the necessity of surgical intervention. Decision to ...