This image shows the replication cycle of HIV/SIV. The virus replicates in the body's own CD4+ T helper cells. In doing so, it introduces its own genetic information into the DNA of the host cell.

To enhance students’ engagement with and deepen their understanding of the concept of life, consider pairing this narrative with the following classroom resources: The HHMI BioInteractive activity ...

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. The HIV-1 virus, like all viruses, ...

On the left is integrase in its “intasome” structure of four identical four-part complexes (pink) that connect to create one 16-part complex that locks around viral DNA (blue). On the right is ...

Researchers at Johns Hopkins Medicine, in collaboration with researchers at the National Institutes of Health, report that two new studies in mice with a humanized immune system and human cell lines ...