Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...
The endoplasmic reticulum (ER) and the secretory pathway are central to the orchestration of intracellular protein trafficking and lipid homeostasis. These dynamic systems comprise a network of ...
Classic studies of temperature-sensitive secretory (sec) mutants have demonstrated that secreted and plasma membrane proteins follow a common SEC pathway via the endoplasmic reticulum (ER), Golgi ...