Boosting mitochondrial calcium by inhibiting the LETM1 protein enhances long-term memory formation in flies and mice.

An international team led by Jaime de Juan-Sanz at the Paris Brain Institute has shown that slightly increasing the metabolic ...

Synaptic transmission is an energy hog. It requires neurons to tap ATP reserves to respond to incoming signals. How do they pull this off, thousands to millions of times per day? A new study ...

Scientists led by a team at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out how a molecular machine found in mitochondria—the “powerhouses” of ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

The evidence is amassing that alterations in brain energy metabolism are the first cause of all psychiatric disorders, from anxiety to schizophrenia, autism to Alzheimer’s disease. The metabolic ...