Nucleoside analogues are modified forms of natural nucleosides that have become indispensable in both therapeutic and diagnostic applications. Their structural alterations enable them to interfere ...
New research has revealed the differences in mechanism behind cancer’s resistance to the major class of anti-cancer drugs known as nucleoside analogues. Nucleosides are molecules containing the ...
- Combination of IMU-838 and N4-Hydroxycytidine Reduced SARS-CoV-2 Virus Levels, Including the Delta Variant, Down to the Detection Limit - The company re-iterates its prior guidance that phase 2 ...
Discovering antiviral and anticancer drugs will soon be faster and cheaper thanks to new research from Simon Fraser University chemist Robert Britton and his international team. For the past 50 years, ...
A subgroup analysis of the East Asia population in RANGE: A randomized phase 3 study of docetaxel (DOC) with or without ramucirumab (RAM) in platinum-refractory advanced or metastatic urothelial ...
In addition, several drugs have been reported occasionally to produce pericarditis 4–12 when administered to man. The mechanism by which they induce the lesion appears to be one of hypersensitivity ...
What's new concerning the hyperlactatemia and lactic acidemia associated with antiretroviral therapy? Find out in this easy-to-navigate compilation of MEDLINE abstracts compiled by the editors at ...
Dr. Logue's research interests are in the application of organic synthesis to carbohydrates, C-nucleosides, and nucleotide analogues. C-nucleosides are nucleosides that contain a carbon - carbon ...
Pritelivir demonstrated numerically improved efficacy relative to foscarnet, and a more favourable safety and tolerability ...
Clin Drug Invest. 2007;27(8):509-531. Because of its poor tolerability, regimen complexity and drug-interaction potential relative to other new NRTIs, use of didanosine has decreased over the last few ...
Bepirovirsen, an investigational antisense oligonucleotide, led to sustained virologic response and a sustained decrease in hepatitis B virus (HBV) DNA, without the need for rescue medication, in ...
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