Thymidine phosphorylase (TP) is often overexpressed in tumours and has a role in tumour aggressiveness and angiogenesis. Here, we determined whether TP increased tumour invasion and whether ...
Background. 5-Fluorouracil (5-FU) is the cornerstone of chemotherapeutic treatment for patients with colorectal cancer. The enzyme thymidine phosphorylase (TP) catalyzes the conversion of 5-FU to its ...
The engineering of sucrose phosphorylase has emerged as a dynamic field that underpins sustainable production methods for value-added compounds derived from sucrose. By tailoring enzyme active sites, ...
Lymph Node Status and TS Gene Expression Are Prognostic Markers in Stage II/III Rectal Cancer After Neoadjuvant Fluorouracil-Based Chemoradiotherapy These data indicate that capecitabine plus ...
This is a preview. Log in through your library . Abstract Glycogen phosphorylase was purified from the phasic adductor muscle of the bay scallop, Argopecten irradians concentricus. Phosphorylase a was ...
In this study we examined whether EU could competitively inhibit uridine phosphorylase (UP) or orotate phosphoribosyl transferase (OPRT), the primary ANA enzymes of 5-FU. Methods: The cytoplasmic ...
The activities of phosphorylase and synthetase in the bundle sheath cells of maize leaves were investigated in plants that as a result of different light-dark treatments contained various amounts of ...
In a recent study published in Nature Metabolism, researchers attempted to identify new genes and molecular pathways that might supply energy when the availability of glucose or other nutrients is ...
McArdle's disease, also known as Glycogen Storage Disease Type V, or GSD5, is a congenital disorder of muscle metabolism. It occurs when the body loses its ability to break down glycogen leading to ...
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