Interesting Engineering on MSN6mon
Scientists finally discover sugar that could cure male pattern baldness
They found that a naturally occurring sugar called 2-deoxy-D-ribose, or 2dDR for short, can boost hair growth by promoting ...
Nature9d
Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation
The loss of endothelial function precedes these vascular alterations. Here we report that activation of poly(ADP-ribose) polymerase (PARP) is an important factor in the pathogenesis of endothelial ...
The Scientist10mon
Prioritizing PARylation in DNA Damage and Repair
Measuring cellular poly ADP-ribosylation can unlock new anticancer strategies and approaches. ADP-ribosylation, the attachment of ADP-ribose to proteins, is a common eukaryotic post-translational ...
PipelineReview.com20h
Pfizer’s TALZENNA® in Combination with XTANDI® Improves Survival Outcomes in Metastatic Castration Resistant Prostate Cancer
NEW YORK, NY, USA I 13, 2025 I Pfizer Inc. (NYSE: PFE) today announced positive results from the Phase 3 TALAPRO-2 study of TALZENNA® (talazoparib), ...
The American Journal of Managed Care10d
Olaparib Leads PARP Inhibitors in Boosting OS for Platinum-Sensitive Recurrent Ovarian Cancer
While all poly ADP-ribose polymerase (PARP) inhibitors improved progression-free survival, olaparib significantly extended overall survival (OS), making it a preferred option.