Scientific evidence shows how the cognitive decline in Alzheimer's disease (AD) is caused by the buildup of amyloid beta proteins, which promote synaptic malfunction. One of the neuropathological ...

Memory formation and maintenance fundamentally rely on intricate molecular processes that regulate synaptic strength. Central to this phenomenon is synaptic plasticity – the capacity of neural ...

Scientific evidence shows how the cognitive decline in Alzheimer’s disease (AD) is caused by the buildup of amyloid beta proteins, which promote synaptic malfunction. One of the neuropathological ...

This study presents a fundamental discovery of how cerebellar climbing fibers modulate plastic changes in the somatosensory cortex by identifying both the responsible cortical circuit and the ...

The complexity of the human brain is unparalleled. Fortunately, thanks to constant progress in neuroscience over the past decades, we have started to make some sense of the human brain. For instance, ...

Three scientists have collectively won The Brain Prize—the largest award for neuroscience—in recognition of their contributions to the science of brain plasticity. Richard Morris, a neuroscientist at ...

A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...

Cognitive decline associated with aging is caused by the loss of cholinergic nerve supply to the hippocampus of our brain. Since the hippocampus is the center of learning and memory, a reduction in ...