New research being presented at the European Congress on Obesity (ECO) in Venice, Italy (12-15 May), and published in the International Journal of Obesity, could help explain why type 2 diabetes is ...

Type 1 diabetes (T1D) is an autoimmune condition where the immune system destroys insulin-producing β-cells in the pancreas. Yet, not all patients lose insulin function at the same pace. Understanding ...

Type 2 diabetes medications, such as sulfonylureas, have been a mainstay of treating the disease since they came on the ...

Hormones are chemical messages that send signals throughout the body. They work slowly and affect body growth, development, metabolism, sexual function, mood, and other functions. Many medications are ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

Insulin is an important hormone that can be found in high concentrations in the human brain. Insulin has been shown to play many different roles within the brain, ranging from neuroprotective effects ...

Formally started in 1971 with the discovery of the insulin receptor, the field of insulin signalling has by now resolved many questions related to the cellular, biochemical foundation of the hormone's ...

Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...

The functions of biomolecules, including lipids, nucleic acids and especially proteins are determined to a great extent by their structure. This structure–function relationship is a foundation of many ...

Researchers identify genetic markers that predict the rate of β-cell failure in type 1 diabetes, facilitating earlier, personalized care strategies Type 1 diabetes (T1D) is an autoimmune condition ...