Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown ...

Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H 2 S) signaling, report researchers from Japan. Heme binding promotes the reaction of H 2 S with the transcription ...

This work shows how NpnNs initiate bacterial transcription. Cryo-EM reveals how nucleobases pair with the template: one in ...

Bacterial transcriptional regulation is a finely tuned process that enables rapid adaptation to fluctuating environmental conditions. At its core, the regulation of gene expression is mediated by ...

An international team of scientists have used advanced microscopy to image how ribosomes recruit to mRNA. Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell ...

Just like us, bacteria are under constant threat of infection by viruses (called phages). We’ve found that many bacteria are armed with sophisticated viral defence systems powered by reverse ...

Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of deaths reported worldwide each year. Caused by the bacterium Vibrio cholerae, ...