Acetate produced from the acetyl-CoA pathway directly allows synthesis of adenosine triphosphate (ATP) through substrate level phosphorylation.

Schug, Z. T. & Peck, B. et al. Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress. Cancer Cell 27, 57–71 (2015) ...

Acetyl-CoA synthetase-2 is an emerging key enzyme for cancer metabolism, which supplies acetyl-CoA for tumor cells by capturing acetate as a carbon source under stressed conditions. However ...

Exhausted T cells were bailing on ACSS2 and relying heavily on ACLY, forcing themselves to use more citrate and less acetate to create acetyl-CoA, despite equal availability of both nutrients.

Cells synthesize acetyl-CoA using nutrients, such as acetate, derived from food. When a threat is detected, cells add acetyl-CoA to certain proteins, ...

Researchers at the University of Illinois Urbana-Champaign have discovered important new clues in the mystery of how an ...

Cells synthesize acetyl-CoA using nutrients, such as acetate, derived from food. When a threat is detected, cells add acetyl-CoA to certain proteins, which then unlock access to the genetic ...

Exhausted T cells were bailing on ACSS2 and relying heavily on ACLY, forcing themselves to use more citrate and less acetate to create acetyl-CoA, despite equal availability of both nutrients.

Regulation of acetyl CoA. The citric acid cycle begins with the reaction that combines the two-carbon acetyl CoA with a four-carbon oxaloacetic acid to produce the six-carbon molecule citrate.

Solidifying its global vinyl acetate monomer (VAM) capabilities, Celanese is initiating a capital-efficient expansion of its VAM production unit at the company’s world-class chemical industrial ...