Later we comment on the metabolic pathways in which the three classes ... to the mitochondrial matrix to be converted into acetyl-CoA in a reaction catalyzed by the multienzyme complex pyruvate ...

These changes were linked to pathways involving cell differentiation ... Notably, butyrate led to a dose-dependent reduction in acetyl-CoA, pointing to a metabolic shift that favors specific ...

Additionally, an alternative metabolism called glycolysis ... resulting in depleted intracellular acetyl-CoA and attenuated activation-induced cell death, or AICD. Restoration of intracellular ...