Everything to know as the defending champions of the Champions League host one of the hottest teams across Europe in a Champions League showdown

Slavia Prague vs Arsenal Highlights, UEFA Champions League 2025-26: Follow the play-by-play updates from the SLA vs ARS match at Fortuna Arena in Prague on November 4, 2025, as it happened

The Liverpool vs Real Madrid UEFA Champions League match will be played at Anfield, Liverpool, England, on Tuesday, November 4.

Kickoff from Anfield in Liverpool is set for 3 p.m. ET. The latest Liverpool vs. Real Madrid odds list the hosts as slight +150 favorites (risk $100 to win $150) on the 90-minute money line, with Real Madrid listed as the +155 underdogs.

Enjoy all the action from Tuesday's UEFA Champions League matches, including Liverpool vs. Real Madrid and Paris Saint-Germain vs. Bayern Munich.

The match bears additional gravity with Madrid's Trent Alexander-Arnold making his return to Anfield after leaving Liverpool over the summer. Alexander-Arnold joined Liverpool's youth academy when he was six years old and played nine seasons with the senior team, winning two Premier League titles and a Champions League crown.

Real Madrid faces Liverpool in the UEFA Champions League on Tuesday, Nov. 4, 2025 (11/4/25) at Anfield in Liverpool, England.

The marquee match-up of this Champions League matchday is Bayern Munich’s visit to Pari Saint-Germain (sorry Liverpool and Real Madrid, this is the best game on the docket). Two of Europe’s most powerful squads will square off in what should be a true battle.