A hallmark of cystic fibrosis, a disease caused by mutations in the CTFR gene, is the accumulation of abnormally thick and sticky mucus in the lung, intestine, and various other organs. Although the ...

cAMP is an evolutionary conserved, prototypic second messenger regulating numerous cellular functions. In mammals, cAMP is synthesized by one of 10 homologous adenylyl cyclases (ACs): nine ...

A CO2 blood test measures the amount of carbon dioxide (CO2) in the blood serum, which is the liquid part of blood. It’s typically used to screen for kidney, respiratory, or metabolic disorders. You ...

The focus of this critical care pearl is to discuss the use of bicarbonate drips for severe metabolic acidosis, as well as alternative options, which are available. Given the current nature of ...

image: Researchers from the University of Tsukuba have identified a new type of carbonic anhydrase enzyme that can convert CO2 to HCO3- without the use of a metal ion. This discovery not only ...

In critically ill patients with severe metabolic acidaemia (defined as pH ≤ 7.20) and moderate-to-severe acute kidney injury (AKI), intravenous sodium bicarbonate infusion did not reduce all-cause ...

(Learn more about excess alkali in the blood in cats. Picture credit: Vasyl Dolmatov / Getty Images) Excess alkali in the blood in cats happens when there’s too much bicarbonate (HCO3) in the blood.