In the early days of President Donald Trump's second term, Alaska Sen. Lisa Murkowski has openly challenged or rebuked him at least three times — stunning for a congressional Republican who has faced his wrath before and yet remains unbowed by pressure to embrace his agenda.

Lisa Murkowski, the senior United States senator from Alaska, has held the seat since 2002. When will she be up for re-election? Here's what we know.

A defining duo of the first Donald Trump administration is back.

U.S. Sen Lisa Murkowski was alone in stridently opposing Trump’s blanket pardon for Jan. 6 defendants, and his order to rename Denali as Mount McKinley.

At the White House, President Donald Trump said he was surprised that two senators have publicly said they'll vote against his nominee to lead the Defense Department.

Pete Hegseth, President Donald Trump's pick to lead the Pentagon, cleared a key procedural hurdle in the Senate on Thursday to advance his nomination.

The Alaska Republican’s decision Thursday comes ahead of a crucial test vote to advance Hegseth’s nomination toward confirmation.

Donald Trump scored a big win in Washington and visited North Carolina, California and Nevada on first trip since beginning his second term.

The Senate confirmed Pete Hegseth as the nation’s defense secretary in a dramatic late-night vote. Republicans pushed back questions about Hegseth's qualifications amid allegations of heavy drinking and aggressive behavior toward women.

The President's order to rename Denali, North America's highest peak, back to Mount McKinley does not agree with Alaska senator.

Sen. Lisa Murkowski is opposing the nomination of Pete Hegseth to be President Donald Trump's Defense secretary.

President Donald Trump has kicked off his second term with a flurry of executive actions on immigration, the economy, DEI and more. Federal agencies are being directed to place all employees working on DEI programs and initiatives to be put on paid administrative leave by Wednesday at 5 p.m.