George Kittle has just 75 yards in the three games that he has played since returning from an injury that sidelined him for ...

Preview the Week 11 NCAA football matchup between the East Carolina Pirates and Charlotte 49ers with a prediction, pick, odds ...

SANTA CLARA, Calif. (AP) — The San Francisco 49ers have been aggressive at the trade deadline in past seasons, trading ...

A storied rivalry will add another significant chapter Sunday when the San Francisco 49ers stare down the Los Angeles Rams at ...

The 49ers are by far the most injured team in the NFL. The only teams playing close to as many rookies as San Francisco are ...

Everything you need to know about the NFL match between San Francisco 49ers and Los Angeles Rams, as well as kick-off time ...

The Rams and 49ers will square off in a rematch of their Week 5 game on Sunday as Los Angeles looks for its seventh win.

We have the bold predictions ready as Matthew Stafford and the Rams face the 49ers in a massive NFC West battle.

If the Los Angeles Rams lose to the San Francisco 49ers in Week 10, it won’t matter if they have almost the same record and ...

Sunday’s noon slate pits the Texans against the Jaguars, plus Ravens-Vikings and Patriots-Buccaneers. Pivotal NFC West ...

SportsLine expert Jeff Hochman breaks down his top money line parlays for favorites and underdogs for Week 10 of the NFL ...

ESPN analyst Dan Orlovsky floated the possibility Brock Purdy may not get his starting job back from Mac Jones once he's ...