In this project, we have seen the active catalyst effect of PdCl2(Ph3P)2 for direct acylation reaction of organotrifluoroborates in good to high yields.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. This study aimed to obtain a derivative of rutin that has biological activities for ...

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Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands ...

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic. However, in recent years, some doctors have prescribed ketamine to treat ...

Trace amine-associated receptor 1 (TAAR1) is a novel, pharmacological target in the treatment of schizophrenia and other neuropsychiatric conditions. Several TAAR1 agonists are currently being ...

This study uses a wide range of approaches to identify acylation as a key regulator of Orai1 channel activation and calcium entry. The results show a novel role for Orai1 acylation in promoting ...

Hydrophobic amino acids of surfactin molecule are located at positions 2, 3, 4, 6, and 7 while hydrophilic glutamyl and aspartyl residues are located at position 1 and 5, giving the molecule two ...

The diversity of life on Earth is a result of continual innovations in molecular networks influencing morphology and physiology. Plant specialized metabolism produces hundreds of thousands of ...