Glycogen storage disease type 1a (von Gierke disease, GSD-1A) is caused by the deficiency of microsomal glucose-6-phosphatase (G6Pase) activity which catalyzes the final common step of ...

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle ...

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle ...

This valuable study presents a novel approach to enhance the therapeutic potential of mesenchymal stromal cells (MSCs) by genetically modifying their glycogen synthesis pathway, resulting in increased ...

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

Crystalline silica is well-known to induce oxidative stress as a consequence of both surface-derived generation of free radicals and intracellular production of reactive oxygen species upon ...

Researchers have uncovered how the breakdown of glycogen may protect the brain from neurodegeneration and Alzheimer's.

AIM To determine whether vitamin K1, which is routinely administered to neonates, could act as an exogenous oxidising agent and be partly responsible for haemolysis in glucose-6-phosphat-dehydrogenase ...

Introduction Plasmodium vivax is the predominant cause of malaria in the Greater Mekong Subregion. To ensure safe treatment with primaquine, point-of-care glucose-6-phosphate dehydrogenase (G6PD) ...

Scientists found that brain cells can tap a hidden sugar stash to clean up the toxic proteins behind Alzheimer’s. By kick-starting an enzyme called GlyP, they reroute stored sugar into a protective ...

Glycogen, a hyperbranched polymer of glucose, plays a central role as an energy reserve across diverse organisms. In Escherichia coli, its biosynthesis is linked not only to energy storage but ...

Truncated aminoglycoside−coenzyme A bisubstrate analogues were efficiently prepared using a convergent approach where the amine and the thiol are coupled in one pot with the addition of a linker, ...