The endoplasmic reticulum (ER)-localized transmembrane proteins IRE1, PERK and ATF6 detect the load of unfolded protein in the lumen of the organelle, serving as stress receptors. They transduce the ...
1 Centre for Exercise and Sport Science, Deakin University, School of Exercise and Nutrition Sciences, Burwood, Victoria, Australia 2 Centre for Physical Activity and Nutrition Research, Deakin ...
Research shows that stress, the body’s response to feeling challenged or threatened, induces or worsens medical conditions, including depression, cardiovascular diseases, neurodegenerative diseases, ...
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