Two-step genome editing enables creation of full-length humanized mouse models

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Alternative RNA splicing tied to schizophrenia-like behaviors in animal models

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...
eLife

Cross-species evaluation of TANGO2 homologs, including HRG-9 and HRG-10 in Caenorhabditis elegans, challenges a proposed role in heme trafficking

Evidence from multiple model systems supports a shift away from heme transport and toward metabolic dysfunction and oxidative stress as key drivers of TANGO2 deficiency.
eLife

A default silencing mechanism restrains stress-induced genes in C. elegans

This valuable study identifies a novel regulator of stress-induced gene quiescence in C. elegans: the multi-Zinc-finger protein ZNF-236. The work provides evidence for an active mechanism that ...
Indy100 on MSN

Scientists have discovered real reason why humans no longer have tails

Around 25 million years ago, an evolutionary split occurred between our ancestors, the precursors of humans and apes, and ...
The Conversation

Great apes are humans’ closest relatives, but many are endangered by illegal trading. Here’s what needs to be done

Prof Matyas Liptovszky is a director of Wilder International, and in a voluntary capacity affiliated with the European Association of Zoos and Aquariums. Great apes are humans’ closest relatives in ...
a-z-animals

This Video Is a Lesson in Why Humans Shouldn’t Interact with Wild Animals

I love a good viral video of a wild animal encounter—providing nobody gets hurt. Well, okay, full disclosure, I don’t mind so much if the human gets a little hurt, particularly as comeuppance for ...