Whether you turn red when drinking alcohol, dislike certain smells, or metabolize drugs differently from others, the ...

An AI-driven computational toolkit, Gcoupler, integrates ligand design, statistical modeling, and graph neural networks to predict endogenous metabolites that allosterically modulate the GPCR–Gα ...

A single base change can create a devastating genetic disorder or a beneficial adaptation, or it might have no effect. How do mutations happen, and how do they influence the future of a species?

Hydration modulates aromatic interactions, explaining why Tyr is a stronger sticker than Phe in aqueous environments like protein condensates but not in the cores of folded proteins.

†This work was supported by the Grayce B. Kerr Endowment to the University of Oklahoma (to support the research of P.F.C.). * To whom correspondence should be addressed. E-mail: [email protected].

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 160 00 Prague 6, Czech Republic Department of Organic Chemistry, Faculty of Science, Charles ...