Cellular structure without a membrane: Researcher discusses how synapses use liquids to create functional separations
The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...
Molecular 3D structure of viral 'copying machine' deciphered
Researchers have shown, for the first time, how the genetic material of the Nipah virus replicates in infected cells. The ...
eLife3d
Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression
Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...
News Medical on MSN9d
Detailed enzyme structure offers path to targeted breast cancer drugs
Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells ...
Tech Xplore on MSN2d
Exploring the device structure of next-gen Cuâ‚‚BaSn(S,Se)â‚„ solar cells
We are excited to share groundbreaking advancements in the realm of solar energy technology, particularly highlighting an emerging thinner-film solar cell: Cu2BaSn(S,Se)4. This innovative solar cell ...
Science Daily18d
Supercomputing illuminates detailed nuclear structure
Researchers have developed a new technique that predicts nuclear properties in record detail. The study revealed how the structure of a nucleus relates to the force that holds it together. This ...
3D Genome Structure Guides Sperm Development
New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop ...
EMBO Press5d
miR-708-5p is elevated in bipolar patients and can induce mood disorder-associated behavior in mice
R-708-5p is a stress-regulated microRNA and a potential biomarker for the differential diagnosis of human mood disorders.
eLife4d
Transcriptional Dynamics Uncover the Role of BNIP3 in Mitophagy during Muscle Remodeling in Drosophila
This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...