Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. J. Clin. Invest. 100, 723–735 (1997). Article Google Scholar Oliver, F.J. et al. Resistance to endotoxic shock ...

A more detailed mechanistic study was attempted including determination of ROS and reactive nitrogen species (RNS, e.g., peroxynitrite) production and the catalase and peroxidase activities were ...

We hypothesise that NO is trapped in the epithelial lining fluid (ELF) of the normal human respiratory tract in bioequivalent forms such as S-nitrosothiols or peroxynitrite and that this trapping ...

Figure 1: Mitochondrial involvement in cell death. Mitochondria are organelles with two well-defined compartments: the matrix, surrounded by the inner membrane (IM), and the intermembrane space ...

Aging is an inevitable progressive decline in physiological organ function that increases the chance of disease and death. The renin–angiotensin system (RAS) is involved in the regulation of ...

Nitric oxide is endogenously released in the airways by nitric oxide synthase. Functionally, two isoforms of this enzyme exist: constitutive and inducible. The former seems to protect airways from ...

State Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China ...

Recent highlights from the journal. We celebrate the winners of the 2024 Nobel Prize in Medicine with a collection of publications focused on microRNA research.