A new study published in Nature Communications reveals a novel approach to mitigating tissue damage caused by Streptococcus ...

Animals, plants and many other living organisms inhale oxygen to "burn" (oxidize) compounds like sugar into CO2 and water—a process during which the energy-rich molecule ATP is produced. Cells require ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Zúñiga believes that interventions that target LDHB or related metabolic pathways could be explored as a way to counteract ...

Liver fibrosis is a major global health concern, developing as a result of chronic liver diseases (CLDs) such as viral ...

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

PDHX acetylation promotes tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression.

Each IFN has a unique metabolic signature, with IFNG being the most associated with activation of the kynurenine pathway. IFNs also show differential relationships with clinical markers of poor ...

pyruvate metabolism. Most genes involved in these metabolic pathways were downregulated during sarcopenia progression. For example, the expression of branched-chain amino acid transaminase 2 ...