-- Zalicus Platform Generating Pipeline of Orally Available Compounds Targeting N-type and T-type Calcium Channels and Selected Sodium Channels Involved in Chronic Pain-- CAMBRIDGE, Mass.--(BUSINESS ...

PHILADELPHIA -- An oral, non-addictive sodium channel blocker safely relieved moderate-to-severe acute pain following surgery, according to phase III data that could support regulatory approval.

ATS 2009, SAN DIEGO—Cystic fibrosis patients may benefit from a new therapy that increases airway hydration, preventing the buildup of mucous, which is a key factor in the disease, according to ...

Mutant Brown-Norway-Katholiek (muBN-Ka) rats are capable of producing kininogens in the liver, but cannot release them into the bloodstream, because of the point mutation of Ala163 to Thr in the ...

Atomic-level studies of the architecture of tiny sodium channel proteins, critical to generating electrical signals that start off each beat of the heart, are imparting striking details about their ...

The process of expressing a wide variety of voltage-gated and ligand-gated ion channels enables nociceptors to transduce receptor potential into single action potentials or multiple action potentials.

Dec 25 (Reuters) - RaQualia Pharma Inc : * Says it and Maruho Co Ltd planed to enter into license agreement, regarding selective Na sodium channel blocker, on Dec. 25 ...

Figure 1: Results obtained with the five-step purification procedure, applied to MS and GBS CSF. Figure 3: Concentrations and effects of the natural factor and two synthetic peptides. Amidation of the ...

Vertex Pharma now has a pair of studies backing up its new drug VX-150, suggesting it can provide opioidlike pain relief without the addiction risks. The positive phase 2 data comes right on the heels ...