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Time-resolved fluorescence resonance energy transfer reveals conformational energetics of a bacterial cyclic nucleotide-gated ion channel.
Single-molecule mRNA and protein quantification, combined with stochastic modelling, uncover a post-transcriptional regulatory mechanism that controls the expression of the extremely low-abundance DNA ...
The combination of histological and microscopic techniques, along with the initial application of finite-difference time-domain (FDTD) modeling to a fossil feather, has resulted in the first recovery ...
The rapid development of pesticide resistance in a mite across wide geographical areas is linked to the independent and repeated emergence of multiple mutations in target genes.
Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane.
Life’s new open access agreements contribute towards a more equitable, inclusive and sustainable system for scientific ...
This study examines a valuable question regarding the developmental trajectory of neural mechanisms supporting facial expression processing. Leveraging a rare intracranial EEG (iEEG) dataset including ...
Several studies have now demonstrated that trained immunity occurs in the airways to several pathogens and products, while its utility is yet to be determined.
Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Horticulture and Landscape Architecture, Southwest University, Chongqing, China ...
This important study provides evidence for dynamic coupling between translation initiation and elongation that can help maintain low ribosome density and translational homeostasis. The authors combine ...
PTBP1 Depletion in Mature Astrocytes Reveals Distinct Splicing Alterations Without Neuronal Features
This study reports important negative results by showing that genetic removal of the RNA-binding protein PTBP1 in astrocytes is not sufficient to induce their conversion into neurons, challenging ...
A region of the brain called the paraventricular thalamus mediates the impact of stress on unlearned fear responses, but is not involved in learned fear behavior.
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