Patients with ATTR-CM had significantly impaired global longitudinal strain and higher mechanical dispersion compared to their first-degree relatives who were not affected by the disease. Increased ...

The treatment could potentially help patients reduce the use of glucocorticoids and immunosuppressants, the authors of the study said. The safety and efficacy of efgartigimod for the treatment of ...

The ODDS score showed strong predictive accuracy for 1-year transplant-free survival across varying levels of disease severity and oxygen needs. Researchers have devised a novel composite score that ...

The revisions include the addition of a boxed warning that describes the risk of serious hepatic injury and acute liver failure as well as possible fatal outcomes and the limitation of the use of the ...

Coramitug is well tolerated and leads to a statistically significant reduction in N-terminal pro-brain type natriuretic peptide (NT-proBNP)—a marker of disease progression in transthyretin-mediated ...

The recurrence analysis found that the presence or absence of the IL36RN gene was not associated with recurrence. The use of biologics, particularly interleukin-36 (IL-36) inhibition, has resulted in ...

Except for FLT-3, these RTKs play a role in ILD pathogenesis. By competitively binding to the adenosine triphosphate-binding pocket of these RTKs, Ofev blocks intracellular signaling cascades ...

Important gains were observed in key areas, including basic theory, transfusion compatibility testing, and clinical transfusion application. A structured 6-month fellowship program in transfusion ...

The ratio of posterior wall thickness to the minimum voltage of QRS complexes in limb leads and several parameters derived from electrocardiography could independently predict ATTR-CM. The ratio of ...

Living with HAE means constant self-education, including connecting with patient groups across social media platforms to share experiences, insights, and lessons learned. As someone living with ...

Getty Images A retrospective analysis of patient health records found that transthyretin stabilizers show clinical benefit in adults with ATTR-CM. Those taking TTR stabilizers had a lower risk of ...