In this emotional video, Oprah Winfrey shares the story of the one person she couldn’t forgive. Her honest reflection sheds ...

"Our biology and genetics set a baseline for our bodies, and for many of us, no amount of diet or exercise will move the ...

Winfrey and Gayle King shared wisdom, jokes and more during an chat at New York’s 92NY on Tuesday. Winfrey drew cheers when ...

Oprah Winfrey surprised an audience when she revealed she once won a drinking contest with 17 shots of tequila ...

Publicly struggling with her weight throughout her career, Winfrey has been a spokesperson for Weight Watchers but has journeyed with GLP-1 weight loss medication for the past two years. It turns out ...

1984: Oprah Winfrey debuted as the new host of “AM Chicago.” A woman fights the wind-blown snow as she tries to cross Wacker Drive near the Chicago River on Jan. 2, 1999. (John Lee/Chicago Tribune) ...

The icon, who has cowritten a new book on obesity, tells PEOPLE that she doesn't recognize the woman she's become—but she's happier and healthier Jamie Green Oprah Winfrey used to view exercise as a ...

A new understanding of her body and her weight has helped the talk show icon "feel more alive and more vibrant than I’ve ever been," without the guilt. After a lifetime of public scrutiny about her ...

Oprah Winfrey shared an update on her weight loss medication experience. She said the injections, for her, will be “a lifetime thing.” She also opened up about how she’s feeling now and her mild side ...

*Oprah Winfrey is opening up about her complicated relationship with GLP-1 weight loss medication and the lessons she learned after briefly walking away from it. In a new PEOPLE cover story, Winfrey ...

This is read by an automated voice. Please report any issues or inconsistencies here. After decades of public and self-imposed shame, Oprah credits a GLP-1 drug with silencing “food noise” — the ...