Background Interferon (IFN)-stimulated gene 15 (ISG15) is a downstream molecule of the IFN pathways central to many cellular processes. ISG15 mainly exerts its function through a post-translational ...

Background: Mechanical thrombectomy has been associated with improved outcomes in patients with acute ischemic stroke. However, not all patients with successful reperfusion experience good functional ...

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be caused by a variety of factors, including metabolic dysfunction-associated ...

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be caused by a variety of factors, including metabolic dysfunction-associated ...

Following publication, concerns were raised regarding the integrity of the images in the published figures. Image duplication concerns were identified in Figures 1A, 2C, 6B. The authors failed to ...

HIV-1 pre-exposure prophylaxis (PrEP) relies on inhibition of HIV-1 replication steps. To understand how PrEP modulates the immunological environment, we derived the plasma proteomic profile of men ...

Cytotoxic T lymphocytes (CTLs) are thought to arrive at target sites either via random search or following signals by other leukocytes. Here, we reveal independent emergent behaviour in CTL ...

Systemic impact on tumor growth after combined immuno-thermal ablation in a murine model of colorectal cancer. This is an ASCO Meeting Abstract from the 2020 Gastrointestinal Cancers Symposium. This ...

A hazardous, ozone-depleting compound is still being used in China, even though it is banned worldwide by the Montreal Protocol, a new study finds. Eastern China has emitted significant amounts of ...

The Frank R. Lautenberg Chemical Safety for the 21st Century Act amends the Toxic Substances Control Act (TSCA) and was signed into law June 22, 2016. It created a mandatory requirement for EPA to ...