Study finds 99% of all heart attacks, heart failure, or strokes occur in people with "suboptimal" blood pressure, cholesterol ...

Objective To develop and validate a novel risk prediction model for incident major adverse liver outcomes (MALO) in a primary care setting. Design Population based cohort study. Setting Sweden, with ...

Benefitting from employer-provided retirement plans, at its most basic, requires two things: employment, and participation in a plan. A recent report provides a look at how that’s worked for a cohort ...

Aim To identify subgroups of early rheumatoid arthritis (RA) based on comorbidities and RA manifestations and to investigate ...

Background Severe mental disorders are associated with increased risk of metabolic dysfunction. Identifying those subgroups at higher risk may help to inform more effective early intervention. The ...

This study highlights how antipsychotic prescribing in dementia is discordant with current NICE guidelines on both duration ...

Background CYP2C19 genotyping has been widely studied to guide antiplatelet therapy in cardiovascular disease; however, its role in neurointerventional procedures, particularly for unruptured ...

Objective To examine the association between nuclear magnetic resonance (NMR)-based metabolomics and aortic stenosis (AS) risk, and determine whether metabolomic profiling can enhance AS prediction ...

BRCA1-Associated Protein 1 and Enhancer of Zeste Homolog 2: Pathway Interaction and Therapeutic Intervention in Breast Cancer, Mesothelioma, and Lymphoma Early-phase clinical trials (EPCTs) have been ...

Hippocampal Avoidance During Prophylactic Cranial Irradiation for Patients With Small Cell Lung Cancer: Randomized Phase II/III Trial NRG-CC003 In this phase IIb parallel cohort study, patients with ...

Background Acute appendicitis requires timely diagnosis. The diagnostic efficacy of tongue examination in making this diagnosis has not been established. This study investigates whether the Tongue ...

Introduction Poverty amplifies the risk of malnutrition, which is particularly harmful to children as it can perpetuate a cycle of poverty and poor health. This study aims to assess the association of ...