President Donald Trump announced "major combat operations" against Iran on Saturday, with daytime strikes in the joint U.S.-Israel attack targeting military and government sites, officials said. On Sunday, Iranian state television confirmed that Ayatollah Ali Khamenei was among those killed by airstrikes in Tehran on Saturday.

The first U.S. casualties of the war with Iran occurred among American personnel based in Kuwait.

Explosions have been heard in multiple Gulf cities including Dubai, Abu Dhabi and Doha, while Israel and Hezbollah are trading blows as the war with Iran widens. Follow for live coverage.

President Donald Trump told CNN on Monday that the U.S. military is “knocking the crap” out of Iran and the “big wave” is yet to come. “We haven’t even started hitting them hard. The big wave hasn’t even happened. The big one is coming soon,” Trump told CNN’s Jake Tapper in a phone call.

The U.S. and Israel struck Iran on Saturday. President Donald Trump said Iran’s Supreme Leader Ayatollah Ali Khamenei is dead, telling Iranians to take back their country.

President Trump said he expects the bombing campaign to last four to five weeks, but "we have [the] capability to go far longer than that."

Iranian Supreme Leader Ayatollah Ali Khamenei was killed in a major attack on Iran launched by Israel and the United States, throwing the future of the Islamic Republic into doubt and raising the

Changing the Iranian regime is “mission impossible,” the country’s foreign minister said in an exclusive interview with NBC News.