They looked for increased expression of other genes and found higher levels of all but one enzyme used in the pentose phosphate pathway (PPP). And blocking the PPP prevented tail regrowth, suggesting ...
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One step closer to reversing liver failure: Study shows how liver is triggered to regrow when damagedMore information: Vicky W.T. Tan et al, SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway, Developmental Cell (2024). DOI: 10.1016/j.devcel.
The pentose phosphate pathway then arms the neutrophils to make NETs. "When we disrupted either glycolysis or the pentose phosphate pathway, neutrophils made fewer NETs.
pentose phosphate pathway for purine biosynthesis, fatty acid metabolism, as well as anaplerotic and mitochondrial gene expression. Importantly, leukemic cells with high basal AKT phosphorylation ...
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