Nature

Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors

Thymidine phosphorylase (TP) is often overexpressed in tumours and has a role in tumour aggressiveness and angiogenesis. Here, we determined whether TP increased tumour invasion and whether ...
JSTOR Daily

Conversion of Glycogen Phosphorylase b to a by Non-Activated Phosphorylase b Kinase: An in vitro Model of the Mechanism of Increase in Phosphorylase a Activity with Muscle ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 67, No. 1 (Sep. 15, 1970), pp. 345-350 (6 pages) ...
JSTOR Daily

The Role of Glycogen Phosphorylase in the Control of Glycolysis during Contractile Activity in the Phasic Adductor Muscle of the Bay Scallop, Argopecten irradians concentricus

This is a preview. Log in through your library . Abstract Glycogen phosphorylase was purified from the phasic adductor muscle of the bay scallop, Argopecten irradians concentricus. Phosphorylase a was ...
Business Wire

Innovo Therapeutics Announces Positive Phase 1 Results for INV-101, a Novel Immuno-Metabolic Modulator for Autoimmune Diseases

Demonstrated strong safety and favorable pharmacokinetics in Phase 1 study A First-in-class oral small molecule modulating immune cell metabolism via glycogen phosphorylase inhibition Once-daily oral ...
ascopubs.org

A phase II trial to evaluate pemetrexed clinical responses in relation to tumor methylthioadenosine phosphorylase (MTAP) gene status in patients with previously treated ...

Assessment of the diagnostic value of microsatellite instability in the urine of bladder cancer patients. This is an ASCO Meeting Abstract from the 2019 Genitourinary Cancers Symposium. This abstract ...
ascopubs.org

Design and rationale of a phase 1 dose-escalation study of AMG 193, a methylthioadenosine (MTA)-cooperative PRMT5 inhibitor, in patients with advanced methylthioadenosine ...

Rationale and design of phase 1 FTIH study of FOXP3 antisense oligonucleotide AZD8701 in patients with selected advanced solid tumors. This is an ASCO Meeting Abstract from the 2022 ASCO Annual ...