A new study published in Nature Communications reveals a novel approach to mitigating tissue damage caused by Streptococcus pyogenes, the flesh-eating bacterium responsible for severe infections such ...

pyruvate metabolism. Most genes involved in these metabolic pathways were downregulated during sarcopenia progression. For example, the expression of branched-chain amino acid transaminase 2 ...

Liver fibrosis is a major global health concern, developing as a result of chronic liver diseases (CLDs) such as viral ...

PDHX acetylation promotes tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression.

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

A detailed review of a 6-month clinical trial further reinforces strong experimental evidence that a ketogenic diet may offer ...

At 1.5 and 2.5 dpc, genes involved in pyruvate and glycolysis were enriched in the proximal region, potentially providing metabolic support for developing ... in the tumor necrosis factor (TNF) ...

This study presents a valuable finding on the importance of the plasma metabolome in glaucoma risk prediction. The authors have used the UK Biobank data to interrogate the association between plasma ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...