BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Zúñiga believes that interventions that target LDHB or related metabolic pathways could be explored as a way to counteract ...

This study presents a valuable finding on the importance of the plasma metabolome in glaucoma risk prediction. The authors have used the UK Biobank data to interrogate the association between plasma ...

Liver fibrosis is a major global health concern, developing as a result of chronic liver diseases (CLDs) such as viral ...

Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's ...

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

PDHX acetylation promotes tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression.

Key Laboratory of Industrial Fermentation Microbiology of the Ministry of Education, Tianjin University of Science & Technology, Tianjin 300457, PR China ...

pyruvate metabolism. Most genes involved in these metabolic pathways were downregulated during sarcopenia progression. For example, the expression of branched-chain amino acid transaminase 2 ...

Understanding these shared metabolic pathways opens new avenues for improving both crop resilience and human nutrition. The study focuses on lysine catabolism. Catabolism, the breakdown of ...