NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Rams and San Francisco 49ers.

The Rams will simply be happy to be back at home and on the west coast after a long road trip. The Rams will have likely had this game circled on the calendar since they lost back in Week 5. That was a game that the Rams should not have lost and they made too many self-inflicted errors in that game.

After playing in four road games, including trips out east to Philadelphia, Nashville, Baltimore, and London over the course of the first seven weeks of the 2025 NFL season, the Los Angeles Rams will spend the entire month of November close to home.

Thursday Night Football schedule, TV channel, time, streaming information for San Francisco 49ers vs Los Angeles Rams NFL Week 5 game on Oct. 2, 2025.

Get the full 49ers Week 10 practice and media schedule ahead of their matchup vs. the Rams, including press conferences and practice times.

The Los Angeles Rams were blessed by the schedule makers of the NFL when they pitted them against the New Orleans Saints after their bye week. Before the season

The Syracuse Orange have added the Fordham Rams to their 2027 football schedule, according to Fordham's official athletics website.