Our kidneys normally maintain acid-base balance by removing acid and reabsorbing bicarbonate. In CKD, this function declines, ...

Bicarbonate management is a critical aspect of treating patients with chronic kidney disease, particularly those receiving haemodialysis. Inefficient kidney function disrupts the natural acid ...

We randomly assigned participants with chronic kidney disease (estimated glomerular filtration rate [eGFR], 30 to 90 ml per minute per 1.73 m 2 of body-surface area), albuminuria (a urinary ...

The cell NAD+/NADH ratio can constrain biomass synthesis and influence proliferation in nutrient-limited environments. However, which cell processes regulate the NAD+/NADH ratio is not known. Here, we ...

Arterial-Blood Studies during Treatment of Severe Refractory Bronchial Asthma in Case 1 on Admission at 7:00 P.M., when the Asthma Was Refractory to Epinephrine and Arninophylline (1), at 8:00 P.M ...

Sodium bicarbonate is the most common treatment, but it has notable limitations, particularly in terms of patient adherence. By Lindsey Zirker, MS, RD ...

After diluting the samples with 100 mM ammonium bicarbonate buffer to a final urea concentration of 1.6 M, proteins were digested by ... 130 Å, 1 mm × 150 mm, Waters) on an Agilent 1260 Infinity HPLC ...

Objective Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise ...