Jan 11, 2020 · As Ebola outbreaks are relatively rare and unpredictable in nature, and due to limited vaccine quantities, the Ervebo vaccine is reserved for outbreak response to protect persons at the highest risk of contracting Ebola virus disease under a “ring vaccination” strategy, which is similar to the approach used to eradicate smallpox.

Jan 24, 2020 · 8 In addition to the two candidate vaccines described above, more recently two other Ebola vaccine programmes have met the initially proposed pre-clinical trial criteria. These are a heterologous combination of two replication deficient recombinant vectors: human adenovirus 26 and modified vaccinia virus Ankara, both expressing ZEBOV GP ...

Nov 12, 2019 · The injectable Ebola vaccine, Ervebo, is manufactured by Merck (known as MSD outside the US and Canada). It has been shown to be effective in protecting people from the Ebola Zaire virus and is recommended by the WHO Strategic Advisory Group of Experts (SAGE) for vaccines as part of a broader set of Ebola response tools.

The vaccine was developed during the West Africa Ebola epidemic of 2014-2016, during which more than 11 000 people lost their lives to the disease. The vaccine was tested in European and African countries at the time and was used under an “expanded access” protocol in the Democratic Republic of Congo.

Oct 18, 2019 · The World Health Organization (WHO) welcomes the European Medicines Agency (EMA) announcement recommending a conditional marketing authorization for the rVSV-ZEBOV-GP vaccine, which has been shown to be effective in protecting people from the Ebola virus. Today’s announcement by EMA, the European agency responsible for the scientific evaluation of medicines developed by pharmaceutical ...

Apr 20, 2023 · WHO prequalifies Ebola vaccine, paving the way for its use in high-risk countries. Good outbreak control relies on applying a package of interventions, including case management, surveillance and contact tracing, a good laboratory service, safe burials and social mobilisation. Community engagement is key to successfully controlling outbreaks.

The unprecedented scale and severity of the EVD epidemic in West Africa in 2014–2016 led to calls for the urgent development and licensing of an Ebola vaccine. A considerable amount of work was subsequently undertaken and a series of international consultations held on related public health issues and on Ebola vaccine development, evaluation ...

Jan 12, 2021 · The Ebola vaccine is reserved for outbreak response to protect people at the highest risk of contracting Ebola – including healthcare and frontline workers. “This is an important milestone. Over the past decade alone we have seen Ebola devastate communities in West and Central Africa, always hitting the poorest and most vulnerable the ...

Since the establishment of ICG Ebola mechanism in 2021, a total 7,370 doses of Ervebo vaccine have been approved by the ICG to respond to two EVD outbreaks in DRC. Accessing ICG Ebola vaccine stocks To request access to ICG Ebola vaccine stocks, the country should submit the Ebola ICG request form, annexes and other required documents, as per ...

Dec 23, 2016 · An experimental Ebola vaccine was highly protective against the deadly virus in a major trial in Guinea, according to results published today in The Lancet. The vaccine is the first to prevent infection from one of the most lethal known pathogens, and the findings add weight to early trial results published last year.