Lithium: Uses, Action, Side Effects & Toxicity
Lithium: Uses, Action, Side Effects & Toxicity
Apr 17, 2013
hubpages.com
Lithium, Salt, & Water? 💊🧂💧 Here’s something important to know, so save it for later! ⭐Lithium carbonate (a medication used often for bipolar disorder) affects the way kidneys concentrate & dilute urine ❓What does this mean? It means changes in salt & water balance in the body, which can lead to ⬆️urination & thirst Educate your patients to: ⭐Consume a balanced amount of sodium in the diet (no sudden/drastic changes!) → This can lead to lithium toxicity or an increased concentration of the dr
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med's go on Instagram: "Lithium toxicity is often precipitated by drugs that reduce renal clearance of lithium, since lithium is almost entirely excreted by the kidneys. Thiazide diuretics like hydrochlorothiazide increase sodium loss, leading to compensatory proximal tubule reabsorption of sodium—and lithium follows the same pathway—causing elevated lithium levels. This can produce confusion, ataxia, slurred speech, and coarse tremor. Other listed medications do not significantly affect lithium
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Lithium has a very narrow therapeutic window, and small changes in kidney function or medications can quickly push levels into the toxic range. One of the most important clinical pearls is remembering the medications and conditions that reduce lithium clearance. A simple way to remember the major culprits is SALT. S – Sodium depletion: dehydration, vomiting, diarrhea, or low sodium intake cause the kidneys to conserve sodium. Because lithium is handled like sodium in the proximal tubule, the kid
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Lithium toxicity alert! Diarrhea, confusion, tremors... Level 2.4 requires immediate action. Hydrate, hospitalize, don't lower the dose. #LithiumToxicity #Pharmacology #MedicalEducation #NurseLife
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