What causes brain zaps? Brain zaps (also known as Antidepressant Discontinuation Syndrome) are part of withdrawal symptoms. They are considered to be an aftereffect when there is some sort of neurochemical alteration within the brain. - Antidepressant withdrawal: When a person stops taking their antidepressant medication, the zaps are a very common sensation to experience. - Eye movements: It has only been speculated that side-to-side eye movements can intensify and provoke brain zaps. - Medicat
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